Motif ID: NFY{A,B,C}.p2

Z-value: 5.523


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma



Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_139084833 6.378 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr9_+_130883199 5.531 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr12_-_120725210 5.401 LOC338799
hypothetical LOC338799
chr19_+_19035792 5.307 NM_178526
SLC25A42
solute carrier family 25, member 42
chr17_+_43374021 4.981 PNPO
pyridoxamine 5'-phosphate oxidase
chr20_-_45418818 4.760 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr17_+_54587882 4.705 PRR11
proline rich 11
chr17_+_43373887 4.684 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr20_-_538909 4.547 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr17_+_54587641 4.489 NM_018304
PRR11
proline rich 11
chr19_+_1442000 4.486 NM_138393
REEP6
receptor accessory protein 6
chr7_+_99974781 4.383 AGFG2
ArfGAP with FG repeats 2
chr7_+_99974720 4.278 NM_006076
AGFG2
ArfGAP with FG repeats 2
chrX_+_47999740 4.146 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr16_-_2204776 4.053 NM_001042371
PGP
phosphoglycolate phosphatase
chr22_+_36384647 3.999 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_-_73371945 3.891 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_23670247 3.887 NM_014573
TMEM97
transmembrane protein 97
chr7_-_156495985 3.849 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr17_-_54587581 3.748 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr17_-_77573974 3.725 NM_144998
STRA13
stimulated by retinoic acid 13 homolog (mouse)
chr6_+_160103500 3.713 ACAT2
acetyl-CoA acetyltransferase 2
chr1_+_42920729 3.650 YBX1
Y box binding protein 1
chr6_+_43005126 3.599 CNPY3
canopy 3 homolog (zebrafish)
chr1_+_42920755 3.579 YBX1
Y box binding protein 1
chr6_-_30792830 3.556 MDC1
mediator of DNA-damage checkpoint 1
chr1_+_42920718 3.529 YBX1
Y box binding protein 1
chr1_+_42920685 3.474 YBX1
Y box binding protein 1
chr14_-_103251497 3.416 NM_001100118
NM_001100119
NM_005432
XRCC3


X-ray repair complementing defective repair in Chinese hamster cells 3


chrX_-_48844929 3.413 NM_007075
WDR45
WD repeat domain 45
chr1_+_144149794 3.408 NM_006472
TXNIP
thioredoxin interacting protein
chr1_+_42920692 3.387 YBX1
Y box binding protein 1
chr17_+_43082273 3.324 NM_002265
KPNB1
karyopherin (importin) beta 1
chr7_-_150305933 3.315 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr1_+_42920683 3.292 YBX1
Y box binding protein 1
chr19_+_54160369 3.251 NM_000146
FTL
ferritin, light polypeptide
chr11_+_61473931 3.246 NM_001139443
NM_004183
BEST1

bestrophin 1

chr15_+_74416156 3.242 NM_145805
ISL2
ISL LIM homeobox 2
chr7_+_156496360 3.222 LOC645249
hypothetical LOC645249
chr17_+_43082302 3.220 KPNB1
karyopherin (importin) beta 1
chr17_-_53950191 3.219 NM_004687
MTMR4
myotubularin related protein 4
chr1_-_148868178 3.188 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chr17_+_73694992 3.183 NM_001010982
NM_001145526
AFMID

arylformamidase

chr2_+_203207912 3.181 FAM117B
family with sequence similarity 117, member B
chr17_-_35827568 3.178 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr11_-_550706 3.140 NM_173573
C11orf35
chromosome 11 open reading frame 35
chr11_-_19219000 3.097 NM_024680
E2F8
E2F transcription factor 8
chr1_-_28113540 3.096 RPA2
replication protein A2, 32kDa
chr2_+_26862416 3.093 CENPA
centromere protein A
chr19_+_54160399 3.093 FTL
ferritin, light polypeptide
chr14_+_23175383 3.063 NM_005794
NM_182908
DHRS2

dehydrogenase/reductase (SDR family) member 2

chr15_+_74416129 3.045 ISL2
ISL LIM homeobox 2
chr15_+_73278285 3.041 C15orf39
chromosome 15 open reading frame 39
chr6_+_43005214 3.002 CNPY3
canopy 3 homolog (zebrafish)
chr7_+_151792052 2.986 LOC100128822
hypothetical LOC100128822
chr1_-_148868671 2.979 ENSA
endosulfine alpha
chr1_-_159257486 2.942 F11R
F11 receptor
chr14_-_22825072 2.929 HOMEZ
homeobox and leucine zipper encoding
chr17_-_73694669 2.926 NM_003258
TK1
thymidine kinase 1, soluble
chr14_-_22825148 2.914 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr22_-_37481857 2.894 NM_015374
SUN2
Sad1 and UNC84 domain containing 2
chr1_-_23729871 2.893 E2F2
E2F transcription factor 2
chr7_+_129497808 2.848 KLHDC10
kelch domain containing 10
chr21_-_39642935 2.847 HMGN1
high-mobility group nucleosome binding domain 1
chr7_+_129497637 2.843 KLHDC10
kelch domain containing 10
chr7_+_149707338 2.831 NM_173680
ZNF775
zinc finger protein 775
chr14_+_28305922 2.821 NM_005249
FOXG1
forkhead box G1
chr11_+_550868 2.777 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr22_-_37481925 2.777 SUN2
Sad1 and UNC84 domain containing 2
chr7_+_129497572 2.770 NM_014997
KLHDC10
kelch domain containing 10
chr2_+_203208064 2.741 NM_173511
FAM117B
family with sequence similarity 117, member B
chr1_+_42920774 2.740 YBX1
Y box binding protein 1
chr19_-_1992862 2.727 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr21_+_39745649 2.704 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr7_-_71515295 2.683 NM_031468
CALN1
calneuron 1
chr19_-_1993022 2.673 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr20_+_47096280 2.634 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr17_+_43081837 2.634 KPNB1
karyopherin (importin) beta 1
chr2_-_96238296 2.629 NM_020151
STARD7
StAR-related lipid transfer (START) domain containing 7
chr5_+_70918856 2.624 NM_022132
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr14_+_23654161 2.612 DCAF11
DDB1 and CUL4 associated factor 11
chr5_+_70918888 2.609 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_+_51968046 2.608 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr17_+_70256518 2.606


chr1_-_148868713 2.594 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr19_+_55398680 2.588 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr16_+_10387412 2.577 ATF7IP2
activating transcription factor 7 interacting protein 2
chr17_-_45196516 2.545 NM_030802
FAM117A
family with sequence similarity 117, member A
chr20_-_31737731 2.539 E2F1
E2F transcription factor 1
chr17_+_77574476 2.533 NM_144999
LRRC45
leucine rich repeat containing 45
chr2_-_96238234 2.525 STARD7
StAR-related lipid transfer (START) domain containing 7
chr1_+_225194560 2.514 NM_020247
ADCK3
aarF domain containing kinase 3
chr19_-_10352212 2.505 NM_003331
TYK2
tyrosine kinase 2
chr1_-_109742020 2.488 NM_002959
SORT1
sortilin 1
chr13_-_29938029 2.488 NM_002128
HMGB1
high-mobility group box 1
chr9_-_94095734 2.484 IARS
isoleucyl-tRNA synthetase
chr1_-_148868535 2.480 ENSA
endosulfine alpha
chr19_-_17377383 2.473 NM_004335
BST2
bone marrow stromal cell antigen 2
chr22_-_21193037 2.469 ZNF280B
zinc finger protein 280B
chr5_+_70918893 2.463 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr17_+_70256397 2.452 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_45196465 2.437 FAM117A
family with sequence similarity 117, member A
chr1_-_195382189 2.422 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr17_-_71747867 2.422 NM_052916
RNF157
ring finger protein 157
chr1_+_51968191 2.413 OSBPL9
oxysterol binding protein-like 9
chr1_+_225194616 2.397 ADCK3
aarF domain containing kinase 3
chr19_-_10352172 2.397 TYK2
tyrosine kinase 2
chr1_+_51968096 2.375 OSBPL9
oxysterol binding protein-like 9
chr21_-_39642880 2.361 NM_004965
HMGN1
high-mobility group nucleosome binding domain 1
chr1_+_225194582 2.349 ADCK3
aarF domain containing kinase 3
chr20_+_47096189 2.346 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr19_-_6375536 2.344 KHSRP
KH-type splicing regulatory protein
chr19_+_54160468 2.341 FTL
ferritin, light polypeptide
chr5_+_70918935 2.339 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr12_-_55013987 2.314 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr13_-_29937966 2.293 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr17_+_4560680 2.293 ARRB2
arrestin, beta 2
chr20_-_31737815 2.289 NM_005225
E2F1
E2F transcription factor 1
chr6_+_160103052 2.286 ACAT2
acetyl-CoA acetyltransferase 2
chr6_+_160102978 2.279 NM_005891
ACAT2
acetyl-CoA acetyltransferase 2
chr21_-_39642808 2.268 HMGN1
high-mobility group nucleosome binding domain 1
chr14_+_23711044 2.263 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr16_+_1772929 2.257 NM_012225
NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr15_+_87919744 2.255 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr1_+_42920635 2.235 NM_004559
YBX1
Y box binding protein 1
chr19_-_6375801 2.229 KHSRP
KH-type splicing regulatory protein
chr1_+_225194622 2.227 ADCK3
aarF domain containing kinase 3
chr1_-_28113817 2.215 NM_002946
RPA2
replication protein A2, 32kDa
chr21_+_44761927 2.215 C21orf90
chromosome 21 open reading frame 90
chr1_-_209915443 2.213 NM_002497
NEK2
NIMA (never in mitosis gene a)-related kinase 2
chrX_+_69591639 2.212 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chr22_+_48740143 2.211 NM_001001852
PIM3
pim-3 oncogene
chr12_+_108495882 2.198 NM_000431
NM_001114185
MVK

mevalonate kinase

chr6_-_31890765 2.192 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr19_-_54350457 2.190 NM_002152
HRC
histidine rich calcium binding protein
chr19_-_12858956 2.188 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr2_+_10180145 2.160 NM_001165931
RRM2
ribonucleotide reductase M2
chr4_-_174492029 2.146 NM_001130688
NM_002129
HMGB2

high-mobility group box 2

chr1_-_148868664 2.141 ENSA
endosulfine alpha
chr19_-_45948211 2.140 C19orf54
chromosome 19 open reading frame 54
chr21_-_39642712 2.134 HMGN1
high-mobility group nucleosome binding domain 1
chr19_-_45948189 2.125 C19orf54
chromosome 19 open reading frame 54
chr8_+_11697588 2.117 NM_004462
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr6_-_33393696 2.115 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr1_-_159257567 2.107 F11R
F11 receptor
chr16_+_1773004 2.096 NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr5_+_44844724 2.087 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr15_+_38520594 2.085 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr2_+_10180304 2.085 NM_001034
RRM2
ribonucleotide reductase M2
chr17_+_70256370 2.080 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr8_-_144762765 2.080 NM_023078
PYCRL
pyrroline-5-carboxylate reductase-like
chr17_+_70256389 2.070 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr22_-_22511173 2.064 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr6_-_26305456 2.060 HIST1H3D
histone cluster 1, H3d
chrX_+_52797004 2.060 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chr14_-_23653965 2.059 NRL
neural retina leucine zipper
chr1_-_148868644 2.048 ENSA
endosulfine alpha
chr10_-_91393610 2.031 NM_138316
NM_148978
PANK1

pantothenate kinase 1

chr12_-_108495663 2.024 NM_052845
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr17_+_70256341 2.008 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr6_+_99389318 2.007 POU3F2
POU class 3 homeobox 2
chr19_-_14108400 2.005 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr6_-_42821761 1.996 TBCC
tubulin folding cofactor C
chr5_+_68498704 1.984 CCNB1
cyclin B1
chr16_-_1772577 1.983 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr19_+_17377502 1.983 LOC100507535
hypothetical LOC100507535
chr6_-_42821790 1.983 TBCC
tubulin folding cofactor C
chr22_-_28992787 1.979 NM_020530
OSM
oncostatin M
chr16_-_10943716 1.973 NM_014015
DEXI
Dexi homolog (mouse)
chr14_-_52088786 1.967 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr16_-_10943656 1.959 DEXI
Dexi homolog (mouse)
chr6_-_25834733 1.943 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr19_-_4293718 1.938 STAP2
signal transducing adaptor family member 2
chr1_+_110683586 1.921 RBM15
RNA binding motif protein 15
chr4_-_105635499 1.920 CXXC4
CXXC finger protein 4
chr6_-_42821815 1.907 NM_003192
TBCC
tubulin folding cofactor C
chr1_+_110683580 1.901 RBM15
RNA binding motif protein 15
chr16_-_1772305 1.899 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_42920889 1.892 YBX1
Y box binding protein 1
chr1_-_25164061 1.889 NM_001031680
RUNX3
runt-related transcription factor 3
chr12_+_122434561 1.886 NM_020382
SETD8
SET domain containing (lysine methyltransferase) 8
chr1_-_151910041 1.883 ILF2
interleukin enhancer binding factor 2, 45kDa
chr14_-_22549168 1.881 NM_001130706
NM_001130708
NM_021944
C14orf93


chromosome 14 open reading frame 93


chr22_-_20419975 1.874 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr1_-_151910080 1.870 ILF2
interleukin enhancer binding factor 2, 45kDa
chr6_-_42821800 1.865 TBCC
tubulin folding cofactor C
chr2_+_111152272 1.859


chr3_+_52543023 1.857


chr1_-_23730298 1.852 NM_004091
E2F2
E2F transcription factor 2
chr1_-_159257595 1.852 NM_016946
F11R
F11 receptor
chr11_-_2677799 1.846 KCNQ1OT1
KCNQ1 overlapping transcript 1 (non-protein coding)
chr19_-_56561444 1.842 NM_001985
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr8_-_145713959 1.841 NM_004260
RECQL4
RecQ protein-like 4
chr1_-_47552238 1.841 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr12_-_120715937 1.840 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr2_-_234427884 1.838 HJURP
Holliday junction recognition protein
chr4_-_2233606 1.832 MXD4
MAX dimerization protein 4
chr20_-_60415729 1.828 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr16_-_10943778 1.822 DEXI
Dexi homolog (mouse)
chr1_-_151910057 1.818 ILF2
interleukin enhancer binding factor 2, 45kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.26 1.69e-28 GO:0007049 cell cycle
2.56 1.53e-27 GO:0022403 cell cycle phase
2.69 1.84e-26 GO:0000278 mitotic cell cycle
2.34 1.12e-24 GO:0022402 cell cycle process
2.55 5.09e-24 GO:0051276 chromosome organization
2.81 3.34e-22 GO:0000279 M phase
1.82 6.52e-21 GO:0006996 organelle organization
3.11 4.00e-20 GO:0000087 M phase of mitotic cell cycle
3.02 6.10e-18 GO:0000280 nuclear division
3.02 6.10e-18 GO:0007067 mitosis
2.92 6.10e-17 GO:0048285 organelle fission
3.30 2.17e-16 GO:0000075 cell cycle checkpoint
2.76 2.19e-16 GO:0010564 regulation of cell cycle process
2.47 4.36e-16 GO:0006325 chromatin organization
3.22 5.12e-16 GO:0071156 regulation of cell cycle arrest
3.94 1.44e-15 GO:0006323 DNA packaging
4.25 2.04e-15 GO:0065004 protein-DNA complex assembly
3.65 3.84e-15 GO:0071103 DNA conformation change
4.11 4.37e-15 GO:0071824 protein-DNA complex subunit organization
3.75 8.11e-15 GO:0006333 chromatin assembly or disassembly
4.36 5.37e-14 GO:0006334 nucleosome assembly
4.24 7.77e-14 GO:0031497 chromatin assembly
2.16 9.41e-14 GO:0051726 regulation of cell cycle
4.13 1.06e-13 GO:0034728 nucleosome organization
1.55 1.09e-13 GO:0090304 nucleic acid metabolic process
1.34 1.07e-12 GO:0044260 cellular macromolecule metabolic process
1.26 1.30e-12 GO:0044237 cellular metabolic process
1.42 3.14e-12 GO:0034641 cellular nitrogen compound metabolic process
2.50 3.14e-12 GO:0051301 cell division
2.61 4.50e-12 GO:0051325 interphase
2.62 5.40e-12 GO:0051329 interphase of mitotic cell cycle
1.45 3.57e-11 GO:0071842 cellular component organization at cellular level
1.44 4.90e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 7.44e-11 GO:0006807 nitrogen compound metabolic process
1.43 1.13e-10 GO:0071841 cellular component organization or biogenesis at cellular level
1.37 6.43e-10 GO:0016043 cellular component organization
3.61 1.15e-09 GO:0007059 chromosome segregation
1.43 1.29e-09 GO:0009058 biosynthetic process
1.35 2.90e-09 GO:0071840 cellular component organization or biogenesis
1.43 7.60e-09 GO:0044249 cellular biosynthetic process
1.22 1.05e-08 GO:0044238 primary metabolic process
3.81 1.52e-08 GO:0000236 mitotic prometaphase
1.11 3.17e-08 GO:0009987 cellular process
1.19 6.58e-08 GO:0008152 metabolic process
1.50 1.62e-07 GO:0034645 cellular macromolecule biosynthetic process
1.88 4.57e-07 GO:0006259 DNA metabolic process
1.48 5.12e-07 GO:0009059 macromolecule biosynthetic process
2.63 8.93e-07 GO:0006260 DNA replication
1.24 9.63e-07 GO:0043170 macromolecule metabolic process
2.09 2.23e-06 GO:0034622 cellular macromolecular complex assembly
1.45 2.77e-06 GO:0016070 RNA metabolic process
1.75 3.61e-06 GO:0065003 macromolecular complex assembly
1.38 8.89e-06 GO:0006355 regulation of transcription, DNA-dependent
1.28 9.25e-06 GO:0031323 regulation of cellular metabolic process
2.04 1.18e-05 GO:0016568 chromatin modification
1.35 1.23e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.88 1.31e-05 GO:0034621 cellular macromolecular complex subunit organization
1.33 1.38e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.65 1.54e-05 GO:0043933 macromolecular complex subunit organization
2.70 1.82e-05 GO:0000082 G1/S transition of mitotic cell cycle
1.36 1.94e-05 GO:0051252 regulation of RNA metabolic process
1.27 2.01e-05 GO:0080090 regulation of primary metabolic process
1.28 2.91e-05 GO:0060255 regulation of macromolecule metabolic process
1.25 3.04e-05 GO:0019222 regulation of metabolic process
1.32 5.93e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 8.50e-05 GO:0010467 gene expression
2.14 8.93e-05 GO:0007346 regulation of mitotic cell cycle
1.32 1.20e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.61 1.50e-04 GO:0033554 cellular response to stress
1.31 2.31e-04 GO:0010468 regulation of gene expression
3.17 2.40e-04 GO:0000216 M/G1 transition of mitotic cell cycle
4.94 2.98e-04 GO:0006271 DNA strand elongation involved in DNA replication
1.77 3.30e-04 GO:0006974 response to DNA damage stimulus
3.96 3.45e-04 GO:0000819 sister chromatid segregation
2.63 3.56e-04 GO:0007093 mitotic cell cycle checkpoint
4.49 5.18e-04 GO:0006695 cholesterol biosynthetic process
1.29 5.59e-04 GO:0031326 regulation of cellular biosynthetic process
1.29 5.65e-04 GO:0009889 regulation of biosynthetic process
2.72 5.90e-04 GO:0000086 G2/M transition of mitotic cell cycle
4.61 8.90e-04 GO:0022616 DNA strand elongation
4.06 1.15e-03 GO:0016126 sterol biosynthetic process
2.63 1.38e-03 GO:0031570 DNA integrity checkpoint
1.90 1.40e-03 GO:0006281 DNA repair
2.19 1.41e-03 GO:0006457 protein folding
2.61 2.50e-03 GO:0051320 S phase
5.82 2.90e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
2.42 2.97e-03 GO:0006310 DNA recombination
2.31 3.10e-03 GO:0010498 proteasomal protein catabolic process
2.31 3.10e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.77 3.77e-03 GO:0000070 mitotic sister chromatid segregation
2.56 5.50e-03 GO:0000084 S phase of mitotic cell cycle
1.61 6.45e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.54 6.70e-03 GO:0007126 meiosis
2.54 6.70e-03 GO:0051327 M phase of meiotic cell cycle
1.62 6.86e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 7.32e-03 GO:0022607 cellular component assembly
2.52 8.14e-03 GO:0051321 meiotic cell cycle
2.81 8.38e-03 GO:0007088 regulation of mitosis
2.81 8.38e-03 GO:0051783 regulation of nuclear division
1.42 1.00e-02 GO:0044248 cellular catabolic process
1.41 1.05e-02 GO:0044085 cellular component biogenesis
1.64 1.23e-02 GO:0044265 cellular macromolecule catabolic process
1.46 1.46e-02 GO:0032774 RNA biosynthetic process
1.90 1.88e-02 GO:0007017 microtubule-based process
1.45 1.95e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
6.92 2.62e-02 GO:0000085 G2 phase of mitotic cell cycle
6.92 2.62e-02 GO:0051319 G2 phase
1.46 3.10e-02 GO:0006351 transcription, DNA-dependent
2.83 3.29e-02 GO:0006261 DNA-dependent DNA replication
1.25 3.39e-02 GO:0044267 cellular protein metabolic process
1.56 3.65e-02 GO:0009057 macromolecule catabolic process
2.43 3.73e-02 GO:0000077 DNA damage checkpoint
1.45 3.80e-02 GO:0031324 negative regulation of cellular metabolic process
1.43 4.32e-02 GO:0009892 negative regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 1.08e-50 GO:0043226 organelle
1.35 1.82e-50 GO:0043227 membrane-bounded organelle
1.31 3.78e-50 GO:0043229 intracellular organelle
1.35 4.50e-50 GO:0043231 intracellular membrane-bounded organelle
1.23 4.77e-46 GO:0044424 intracellular part
1.22 2.97e-42 GO:0005622 intracellular
1.48 1.39e-39 GO:0005634 nucleus
3.02 1.80e-37 GO:0005694 chromosome
1.46 2.95e-36 GO:0044446 intracellular organelle part
1.45 1.42e-35 GO:0044422 organelle part
3.08 6.89e-33 GO:0044427 chromosomal part
1.74 1.82e-27 GO:0070013 intracellular organelle lumen
1.71 1.66e-26 GO:0031974 membrane-enclosed lumen
1.71 5.25e-26 GO:0043233 organelle lumen
1.69 8.04e-23 GO:0044428 nuclear part
1.48 1.32e-20 GO:0032991 macromolecular complex
3.31 5.07e-20 GO:0000785 chromatin
1.71 1.42e-19 GO:0031981 nuclear lumen
1.53 4.36e-18 GO:0043228 non-membrane-bounded organelle
1.53 4.36e-18 GO:0043232 intracellular non-membrane-bounded organelle
1.79 1.51e-16 GO:0005654 nucleoplasm
1.20 4.97e-14 GO:0005737 cytoplasm
3.98 2.41e-12 GO:0032993 protein-DNA complex
1.41 5.78e-12 GO:0043234 protein complex
4.78 8.35e-12 GO:0000786 nucleosome
3.08 1.03e-11 GO:0044454 nuclear chromosome part
2.83 1.65e-11 GO:0000228 nuclear chromosome
3.25 3.40e-11 GO:0000775 chromosome, centromeric region
3.25 6.34e-11 GO:0000793 condensed chromosome
1.23 1.25e-10 GO:0044444 cytoplasmic part
1.90 3.56e-10 GO:0015630 microtubule cytoskeleton
1.82 1.74e-08 GO:0044429 mitochondrial part
1.55 4.79e-08 GO:0005739 mitochondrion
2.62 1.04e-07 GO:0005819 spindle
3.42 1.91e-06 GO:0000779 condensed chromosome, centromeric region
3.22 2.53e-06 GO:0000776 kinetochore
3.78 1.40e-05 GO:0000794 condensed nuclear chromosome
1.65 1.62e-05 GO:0044451 nucleoplasm part
2.05 2.35e-05 GO:0005874 microtubule
3.39 3.19e-05 GO:0000922 spindle pole
7.06 3.39e-05 GO:0042613 MHC class II protein complex
3.25 4.28e-05 GO:0000777 condensed chromosome kinetochore
2.05 1.58e-04 GO:0005759 mitochondrial matrix
1.04 2.76e-04 GO:0044464 cell part
1.04 2.86e-04 GO:0005623 cell
1.58 3.52e-04 GO:0031967 organelle envelope
1.31 6.91e-04 GO:0005829 cytosol
1.55 8.22e-04 GO:0031975 envelope
1.66 1.25e-03 GO:0030529 ribonucleoprotein complex
1.98 3.24e-03 GO:0016604 nuclear body
1.65 3.86e-03 GO:0005740 mitochondrial envelope
4.71 6.14e-03 GO:0000795 synaptonemal complex
6.29 1.12e-02 GO:0000780 condensed nuclear chromosome, centromeric region
1.88 1.86e-02 GO:0005813 centrosome
3.15 3.09e-02 GO:0000792 heterochromatin
2.83 4.11e-02 GO:0016605 PML body
1.36 4.16e-02 GO:0044430 cytoskeletal part
9.89 4.84e-02 GO:0000800 lateral element

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 2.72e-19 GO:0003676 nucleic acid binding
1.56 2.51e-16 GO:0003677 DNA binding
1.12 7.66e-14 GO:0005488 binding
1.16 8.72e-07 GO:0005515 protein binding
1.57 5.24e-06 GO:0030528 transcription regulator activity
2.27 1.23e-04 GO:0003682 chromatin binding
1.47 9.48e-04 GO:0001071 nucleic acid binding transcription factor activity
1.47 9.48e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.46 2.26e-02 GO:0019899 enzyme binding
2.78 2.89e-02 GO:0008094 DNA-dependent ATPase activity
1.14 2.95e-02 GO:0003824 catalytic activity
1.43 3.32e-02 GO:0003723 RNA binding